Pesticide intermediate development trend

In order to meet China's pesticide development, pesticide product structure adjustment requirements, and to shorten the gap with the foreign pesticide industry, pesticide intermediates will focus on the development of the following products: pesticide intermediates that cannot be produced domestically, and intermediates for high-toxicity pesticide replacement products, including Heterocyclic pesticide intermediates, fluorine-containing pesticide intermediates, and chiral pesticide intermediates.

1. Pesticide Intermediates Containing Heterocycles (1) Intermediates of Heterocyclic Organophosphorus Insecticides, including intermediates of diazinon, chlorpyrifos, quinoline phosphorus, methicillin, and methicone. (2) Intermediates of high-effective insecticides containing heterocyclic rings, including intermediates of imidacloprid, imidacloprid, fipronil, chlorfenapyr. (3) Intermediates of highly effective fungicides containing heterocyclic rings include quinoxaline and furazolidone intermediates. (4) Intermediates containing heterocyclic herbicides, including general sulfonylurea herbicide intermediates, intermediates of imidazolinone herbicides imazethapyr, imazaquin, and triclopyr, quinclorac , thiadiatum intermediates.

2. Fluorine-containing pesticide intermediates In the search for ways to improve biological activity, fluorine is often used instead of hydrogen or chlorine. This kind of substitution can greatly improve the efficacy of pesticides. The introduction of fluorine atoms in the pyrethroid structure will increase the efficacy of pests and have a killing effect. Therefore, fluorine-containing pyrethroids have attracted attention. However, to prepare the most active compound it is necessary to select the fluoro-position of the molecule. Insertion of fluorine atoms plays a key role in biological activity, but fluorine-substituted hydrogen often reduces the activity. However, the most active compounds often contain fluorine atoms at certain positions in the molecular structure. At the same time, it is necessary to prepare highly active fluorine-containing compounds. There are fluorine-containing intermediates, so it is necessary to research and develop fluorine-containing intermediates.