U.S. Experts Find “Elixir” to Extend Rats/3 Lifespan

Lu Jiayi

A new study released by Nature magazine on the 8th said that researchers in the United States have found that a commonly used immunosuppressive drug can prolong the lifespan of rats up to 1/3. This is the first time that such drugs can prolong the life span of mammals and provide a glimmer of hope for human aging.

This drug called rapamycin is usually used to prevent rejection after organ transplantation. After the drugs were used in 20-month-old rats (equivalent to humans 60 years old), their average life span was 28% longer than that of normal mice; the effect on female rats was more pronounced, and the life extension was 38%.

Alan Richardson, head of the Longevity and Aging Institute at the University of Texas, said: "I never expected that we would find medicines for longevity in our lifetime. However, rapamycin demonstrates this possibility."

Although studies have shown that rapamycin prolongs the lifespan of experimental mice, it is too early to talk about "longevity drugs" for humans.

Rapamycin is derived from the soil on the mysterious Easter Island. It has a strong inhibitory effect on the human immune system and is therefore commonly used in patients after organ transplantation. For healthy people, its danger far outweighs the benefits. In addition, the amount of medication is also a problem. The dose of rapamycin in humans is usually 2 mg to 5 mg per day, while that in rats is 2.24 mg per kg of body weight per day.

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